• 王飞虎

    博士,长聘教轨副教授,博士生导师,获国家优秀青年人才项目,上海市海外高层次引进人才。2016年博士毕业于欧洲杯压住平台和中国医药工业研究院,获医学博士学位。同年博士后获聘于约翰霍普金斯大学,先后师从Honggang Cui教授和Justin Hanes 教授。2021年通过绿色人才引进通道受聘于欧洲杯压住平台。主要研究方向包括智能药物递送系统、免疫治疗制剂和中药创新制剂的开发并用于肿瘤、自身免疫性疾病和神经损伤等重大疾病的精准治疗。相关成果在Nat. Biomed. Eng., PNAS, Sci. Adv., ACS Nano, Adv. Drug Delive. Rev., JACS, Angew. Chem., Biomaterials, J. Control. Release 等国际权威学术期刊上发表研究论文50 余篇。对于有良好临床转化潜力的研究成果已申请8项PCT 或中国专利。承担国家重点研发计划、国家自然科学基金、上海市科学技术委员会基金等项目。现任上海市药学会药剂专业委员会青年委员、纳米肿瘤学专业委员会青年委员并担任《生物医学工程学进展》杂志青年编委、《Nano-Micro Letters》青年编委、《Asian Journal of Pharmaceutical Sciences》青年编委、《Exploration》青年编委和《Frontiers in Bioengineering and Biotechnology》客座编辑等。


教育背景

2005.09-2009.07   理学学士, 西安交通大学

2009.09-2012.06   工学硕士, 山东大学

2012.09-2016.06   医学博士, 欧洲杯压住平台和中国医药工业研究院

工作经历

2016.07-2021.05    博士后研究员,约翰霍普金斯大学

2021.06-至今         长聘教轨副教授,博士生导师,欧洲杯压住平台

研究方向

新型药物递送系统

多肽-药物偶联物和超分子药物

免疫工程与免疫治疗

中药创新制剂

科研项目



代表性论文专著

1.     Feihu Wang*, Hao Su, Zeyu Wang, Caleb F. Anderson, Xuanrong Sun, Han Wang, Philippe Laffont, Justin Hanes*, Honggang Cui*. Supramolecular Filament Hydrogel as a Universal Immunomodulator Carrier for Immunotherapy Combinations. ACS Nano, 2023 https://doi.org/10.1021/acsnano.3c01748.

2.     Feihu Wang, Qian Huang, Hao Su, Mingjiao Sun, Zeyu Wang, Ziqi Chen, Mengzhen Zheng, Rami W. Chakroun, Maya K. Monroe, Daiqing Chen, Zongyuan Wang, Noah Gorelick, Riccardo Serra, Han Wang, Yun Guan, Jung Soo Suk, Betty Tyler, Henry Brem, Justin Hanes, and Honggang Cui. Self-assembling paclitaxel-mediated stimulation of tumor-associated macrophages for postoperative treatment of glioblastoma. Proceedings of the National Academy of Sciences,2023,e2204621120.

3.     Qi Shang, Yabing Dong, Yun Su, Faith Leslie, Mingjiao Sun, Feihu Wang*, Local scaffold-assisted delivery of immunotherapeutic agents for improved cancer immunotherapy, Advanced Drug Delivery Reviews, 185 (2022), 114308.

4.     Feihu Wang*, Hao Su, Dongqing Xu, Maya K Monroe, Caleb F Anderson, Weijie Zhang, Richard Oh, Zongyuan Wang, Xuanrong Sun, Han Wang, Fengyi Wan, Honggang Cui*, Therapeutic supramolecular tubustecan hydrogel combined with checkpoint inhibitor elicits immunity to combat cancer, Biomaterials, 279 (2021), 121182.

5.     Feihu Wang, Hao Su, Dongqing Xu, Wenbing Dai, Weijie Zhang, Zongyuan Wang, Caleb Aderson, Mengzhen Zheng, Richard Oh, Fengyi Wan, Honggang Cui. Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel. Nature Biomedical Engineering. 4 (2020), 1090-1101.

6.     Feihu Wang, Dongqing Xu, Hao Su, Weijie Zhang, Xuanrong Sun, Maya. K. Monroe, Rami W. Chakroun, Zongyuan Wang, Wenbing Dai, Richard Oh, Fengyi Wan, Honggang Cui. Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker-based immunotherapy. Science Advances. 6 (2020), eaaz8985.

7.     Feihu Wang, Hao Su, Ran Lin, Rami Chakroun, Maya Monroe, Zongyuan Wang, Michael Porter, Honggang Cui. Supramolecular tubustecan hydrogel as chemotherapeutic carrier to improve tumor penetration and local treatment efficacy. ACS Nano. 14 (2020), 10083-10094.

8.     Hao Su, Feihu Wang, Wei Ran, Weijie Zhang, Wenbing Dai, Han Wang, Caleb Anderson, Zongyuan Wang, Chao Zheng, Pengcheng Zhang, Yaping Li, Honggang Cui. The role of critical micellization concentration in efficacy and toxicity of supramolecular polymers. Proceedings of the National Academy of Sciences. 117 (2020), 4518-4526 (Co-first author).




所有文章列表:https://scholar.google.com/citations?user=WMsl0_kAAAAJ&hl=en

联系方式

邮箱地址:fhwang21@sjtu.edu.cn

办公地址:国家转化医学大楼N310