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  林俐

  长聘教轨助理教授，博士生导师，上海市“晨光计划”学者。于欧洲杯压住平台获学士和博士学位；之后分别在上海交大和伊利诺伊大学香槟分校开展博士后研究。曾获SERS国际会议最佳墙报奖、IMCO2019国际会议最佳论文奖等。在Advanced Science, Small Methods, Nano Letters, ACS Nano等期刊上发表高水平论文，被引900余次，担任多个SCI期刊的审稿人（包括IEEE, ACS, Elsevier, SpringerNature 等出版社期刊）。主持或参与多项国家自然基金项目、省部级和校级项目的研究。近年来的研究兴趣集中在基于光学方法的无创病灶定位和重建，包括拉曼响应纳米探针的设计开发、深穿透拉曼光谱技术和拉曼光学图像重建。开发活体透射拉曼光谱技术，实现了深穿透检测、定位和成像等一系列研究。

  
  

  欢迎生医工、光学、化学和材料领域的硕士、博士以及博士后加入课题组！欢迎对科研感兴趣的本科生提前加入实验室。近年已多次指导本科生国自然基金、毕业设计、国家级大创项目等，并指导本科生团队获“挑战杯”科创竞赛全国特等奖。可直接Email 联系我。

  
  

  招生：2024入学的博士和硕士名额均已满。

基于深穿透光谱技术的活体无创光学成像

基于拉曼光谱的肿瘤快速诊断及预后分析

等离激元金属纳米基底及探针溶胶的设计与开发

1. 国家自然科学基金面上项目，课题负责人，2024-2027

“基于深穿透拉曼光谱的安全光照剂量的深层病灶无创检测与深度估测”

2.欧洲杯压住平台医工交叉研究基金青年项目，合作方负责人， 2022-2024

“基于机器学习算法和光纤拉曼光谱系统的胃癌快速诊断研究”

3.上海市科委“科技创新行动计划”高新技术领域项目，子课题负责人，结题

”基于肿瘤拉曼光活检的新型纤微医疗机器人的研究“

4. 上海市教委“晨光计划”，课题负责人，结题

5. 国家自然科学基金青年基金，课题负责人，结题

Featued Articles After 2021 

1.   Li Lin*, Haoqi He, Ruiyang Xue, Yumin Zhang, Ziwen Wang, Shuming Nie*, Jian Ye*. Direct and quantitative assessments of near‑infrared light attenuation and spectroscopic detection depth in biological tissues using surface‑enhanced Raman scattering. Med-X, 2023, 1, 9.

2.    Zongyu Wu, Binge Deng, Yutong Zhou, Haoqiang Xie, Yumin Zhang, Li Lin*, Jian Ye*. Non-invasive detection, precise localization, and perioperative navigation of in vivo deep lesions using transmission Raman spectroscopy. Advanced Science. 202301721. (IF=17.2)

3.  Yumin Zhang, Li Lin*, Jian Ye*. A rapid and universal method for depth estimation of lesions in heterogeneous tissues via photosafe ratiometric transmission Raman spectroscopy. View, 2023, 20230022. (IF=8.6)

4.    Yumin Zhang, Ruoyu Chen, Fugang Liu, Peng Miao, Li Lin*, and Jian Ye*. In Vivo Surface-Enhanced Transmission Raman Spectroscopy under Maximum Permissible Exposure: Toward Photosafe Detection of Deep-Seated Tumors. Small Methods, 2023, 7(2), 2201334. (IF=15.2)

5.    Li Lin, Ruiyang Xue, Shuming Nie. "Surface-enhanced Raman scattering (SERS) nanoparticles for biodiagnostics, bioimaging, and spectroscopy-guided cancer surgery", In: Reference Module in Materials Science and Materials Engineering, Elsevier, 2022. (Invited Book Chapter)

6.   Haoqi He, Yumin Zhang, Shuo Zhu, Jian Ye*, and Li Lin*. "Resonant strategy in designing NIR-II SERS nanotags: a quantitative study." The Journal of Physical Chemistry C, 2022, 126, 12575. (IF=4.2)

7.   Yao Lu, Li Lin*, Jian Ye*, “Human metabolite detection by surface-enhanced Raman spectroscopy”, Materials Today Bio, 2022, 13, 100205. (IF=10.5)

8.   Li Lin, Jian Ye, “Spontaneous Raman and Surface-Enhanced Raman Scattering Bioimaging.” In: Wei X., Gu B. (eds) Optical imaging in Human Disease and Biological Research. Advances in Experimental Medicine and Biology, vol 3233. Springer, Singapore, 2021, pp177-195. (Invited Book Chapter)

Featured Articles Before 2021

1.   Yuqing Gu, Chang He, Yuqing Zhang, Li Lin, Benjamin David Thackray, Jian Ye*, “Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels”, Nature Communications, 2020, 11, 516. (IF=13.8)

2.   Li Lin, Qiang Zhang, Xiyao Li, Meng Qiu, Xin Jiang, Hongchen Gu*, Dang Yuan Lei*, Jian Ye*, “Electron Transfer in Plasmonic Nanogaps Interrogated with Surface-Enhanced Raman Scattering,” ACS Nano, 2018, 12, 6492. (IF=15.8)

3.   Li Lin, Zhonghui Liu, Xiyao Li, Hongchen Gu, Jian Ye*, “Quantifying the Reflective Index of Nanometer-Thick Molecular Layers on Nanoparticle,” Nanoscale, 2017, 9, 2213. (IF=7.2)

4.    Li Lin, Mario Zapata, Min Xiong, Zhonghui Liu, Shanshan Wang, Hong Xu, Andrei G. Borisov, Hongchen Gu, Peter Nordlander*, Javier Aizpurua*, Jian Ye*, “Nanooptics of Plasmonic Nanomatryoshkas: Shrinking the Size of a Core–Shell junction to Subnanometer,” Nano Letters, 2015, 15, 6419. (IF=11.1)

光学纳米材料的生物医学应用，春季学期

医学工程的伦理及学术规范（面向医工方向博士），秋季学期

生物医学工程学术前沿（面向医工方向博士），秋季学期